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Research & Development

 
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Microbide prides itself on research & development

Our industry-wise team, each with deep experience in the pharmaceutical and medical device industry, is providing the consultative basis to develop the technology for various uses and applications including hospital decontamination, agricultural applications, water and waste water treatment. 

We commission independent testing of our products and set high benchmarks to prove the effectiveness and safety meet the industry requirements. We conduct field trials to confirm the results in the lab, followed by stringent safety tests.

The Microbide team is passionate about the science and the effectiveness of our products. Our breakthrough technology has been patented across the globe. Our growing portfolio of applications are driven by the demand of regulators, industry and communities for safer solutions.

 
 

A chemical with potential 

 
 

Mary Skelly, CEO first filed a patent for the technology in 2008. A year later, following successful antimicrobial tests on bacteria and spores, she decided to trial it on mosquitoes.

The formula was tested on Anopheles arabiensis, one of the mosquito species that carries malaria, and Aedes aegypti, the major culprit in Zika transmission. The results showed that the micellized aldehyde solutions were highly effective at killing the immature stages of both species of mosquito.

The complexed aldehydes have also outperformed non-complexed market leaders in head-to-head studies of hospital high level disinfectants.

The true advantage is the environmentally friendly nature of the solution. The product is entirely biodegradable – after use it breaks down into CO2 and water.

The Microbide solutions are pH neutral and studies show the active aldehydes have no effect on larger organisms found in water, such as fish, plants and even adult mosquitoes.

 

There is an urgent need for better disinfection and bio-hazard control options that can address a broad range of bio-safety challenges occurring around the globe. 

Microbide hopes to reduce HAI (Hospital Acquired Infections) with their Microbide-HLD (High Level Disinfectant) range of products, used for cleaning invasive medical equipment such as endoscopes, surgical equipment and hard surface cleaners.

Microbide has joined the fight to reduce vector-borne diseases such as Zika Virus, Dengue Fever and Malaria carried by mosquitos by creating a solution that is highly effective at killing mosquito larvae and trialling it's effectiveness in Pune and Goa (India).

Microbide is also in working to combat Avian Influenza (AI) and other such disease that effect our food supply. AI poses potential threats to human health as AI viruses have previously transmitted across species to humans.  Current testing has proved successful with the two strains of avian flu, H5N1 and H9N2.

 

4 million

 patients in the European Union suffer at least one HAI (Hospital Acquired Infection) annually, contributing to 110,000 deaths

OECD


17%

of all infectious disease are vector borne diseases, causing more than 700,000 deaths annually

WHO


400,000

Deaths every year globally from Malaria

WHO


96 million

estimated cases of Dengue Fever per year

WHO

 

Chemistry 101

Aldehydes and their biocidal capabilities

 
 

Aldehyde: 

Aldehydes are organic compounds containing a carbonyl group, ( -CHO) a carbon double bonded to oxygen bonded to hydrogen and another group. By definition, the aldehyde carbonyl group must always lie at the end of a carbon chain in order to provide both the –OH and –H components of the carbonyl. The C=O bond (double bond) is highly polar.

Aldehydes are widespread in nature, and are derived from both plants and animals. The aldehydes are very reactive.

Di-Aldehyde: 

Aldehydes exist as mono- and di- aldehydes, having one or two reactive moieties respectively. Many of the di-aldehydes are derived from petrochemicals.

Biocidal capacity of aldehydes

The biocidal capacity of aldehydes depends on the environment in which it is used, particularly: the target organism or microbial ecosystem, the concentration, contact time, pH and temperature.

In order to harness the biocidal capacity of various aldehydes, Microbide uses a patented process to 'complex' the active aldehyde ingredient with a number of inactive ingredients to hold the aldehyde in solution and reduce its volatility. By associating various aldehydes with surfactants and other biodegradable ingredients, the aldehyde is protected by its association in micellular structures. The micelles directionally point the active carbonyl group of the aldehyde toward the surface of the solution; thereby making the aldehyde biocide far more effective at killing germs.

 

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  Microbide  uses a patented process to 'complex' the active aldehyde ingredient with a number of inactive ingredients to hold the aldehyde in solution and reduce its volatility.

Microbide uses a patented process to 'complex' the active aldehyde ingredient with a number of inactive ingredients to hold the aldehyde in solution and reduce its volatility.

Microbide Micellised Products

Microbide’s solutions are developed at neutral pH for each active aldehyde ingredient. There is no requirement for activation prior to use.

Head-to-head comparative studies of Microbide’s complexed aldehydes versus their non-complexed market leading counterparts demonstrate significant improvement in efficacy, together with a reduced volatility profile and improved safety.

Microbide are developing a series of both complexed mon- and complexed di- aldehydes and combination products to address specific microbial control issues.

The majority of our product range is biodegradable with the exception of Microbide-O: a HLD is our only non-biodegradable product. In general most aldehydes with ring structures (for example ortho-phthalaldehyde) are not readily biodegradable.

 
 
 

Interested in what we are doing?

 
 
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